Staff Profile: Jaroslaw Krzywinski
Jaroslaw Krzywinski PhD
Areas of interest: Vector systematics, mosquito genomics
Jarek Krzywinski earned his MSc and PhD from the University of Gdansk (Poland), based on the studies of nectar feeding in biting midges (Ceratopogonidae) and morphology-based taxonomy and systematics of predaceous ceratopogonids. He held postdoctoral positions at the University of Gdansk and, then, the University of Notre Dame, USA (1998-2004), where he was researching molecular systematics and genomics of anopheline mosquitoes. At Notre Dame he was promoted to a research assistant professor in 2004. In 2005 he assumed an assistant professorship in bioinformatics and genomics at the University of Texas, Arlington. Jarek joined the LSTM Vector Group in 2007.
Lecturing and small group teaching on vector biology in post-graduate Masters programmes in Biology and Control of Parasites and Disease Vectors andMolecular Biology of Parasites and Disease Vectors and the Diploma of Tropical Medicine and Hygiene at LSTM and the BSc programme in Tropical Biology (University of Liverpool).
Developmental regulation of gene expression.
Systematics of nematoceran biting flies from the families Culicidae and Ceratopogonidae (Diptera).
Nathan Dennison, PhD student, Regulation of gene expression in early development of mosquitoes (Co-supervised with Dr Gareth Lycett)
Current Grants and Projects
Wellcome Trust (2010-2013) £267,710 "Functional genetic and transcriptomic analysis of male fertility in Anopheles gambiae"
Krzywinska, E., Krzywinski, J., 2009. Analysis of expression in the Anopheles gambiae developing testes reveals rapidly evolving lineage-specific genes in mosquitoes. BMC Genomics, 10:300.
Sharakhova, M.V., Hammond, M.P., Lobo, N.F., Krzywinski, J., Unger, M.F., Hillenmeyer, M.E., Bruggner, R.V., Birney, E., Collins, F.H. 2007. Update of the Anopheles gambiae PEST genome assembly. Genome Biol. 8(1): R5.
Krzywinski, J., Chrystal, M.A., Besansky, N.J. 2006. Gene finding on the Y: fruitful strategy in Drosophila does not deliver in Anopheles. Genetica 126:369-75.
Krzywinski, J., Grushko, O.G., Besansky, N.J. 2006. Analysis of the complete mitochondrial DNA from Anopheles funestus: an improved dipteran mitochondrial genome annotation and a temporal dimension of mosquito evolution. Mol Phylogenet Evol. 39: 417-23.
Krzywinski, J., Sangare, D., Besansky, N. J. 2005, Satellite DNA from the Y chromosome of the malaria vector Anopheles gambiae. Genetics. 169: 185-196.
Krzywinski, J., Nusskern, D. R., Kern, M. K., Besansky, N. J., 2004, Isolation and characterization of Y chromosome sequences from the African malaria mosquito Anopheles gambiae. Genetics, 166: 1291-1302.
Besansky, N. J., Krzywinski, J., Lehmann, T., Simard, F., Kern, M., Mukabayire, O., Fontenille, D., Toure, Y., Sangon, N'F., 2003, Semipermeable species boundaries between Anopheles gambiae and Anopheles arabiensis: Evidence from multilocus DNA sequence variation. PNAS. 100: 10818-10823.
Sarkar, A., Sengupta, R., Krzywinski, J., Wang, X., Roth, C., Collins, F. H.,, 2003, P elements are found in the genomes of nematoceran insects of the genus Anopheles. Insect Biochem. Mol. Biol. 2003 33: 381-7.
Krzywinski, J., Besansky, N. J., 2003, Molecular systematics of Anopheles: From subgenera to subpopulations. Annu. Rev. Entomol. 48: 111-139.
Krzywinski, J., Besansky, N. J., 2002, Frequent intron loss in the white gene: A cautionary tale for phylogeneticists. Mol. Biol. Evol. 19: 362-366.
Krzywinski, J., Wilkerson, R. C., Besansky, N. J., 2001, Toward understanding Anophelinae (Diptera, Culicidae) phylogeny: Insights from nuclear single copy genes and the weight of evidence. Syst. Biol. 50: 540-556.
Krzywinski, J., Wilkerson, R. C., Besansky, N. J., 2001, Evolution of mitochondrial and ribosomal gene sequences in Anophelinae (Diptera: Culicidae): implications for phylogeny reconstruction. Mol. Phylogenet. Evol. 18: 479-487.